Robert Kubica will not be allowed to race at the United States Grand Prix following his massive crash in Canada last Sunday.
The Pole will be replaced by BMW Sauber's test driver Sebastian Vettel, who will make his Grand Prix debut this weekend at the age of 19.
Kubica crashed heavily during the Canadian Grand Prix, his car being destroyed after impacting against the wall at very high speed.
Although the Pole spent the night in hospital, he was released on Monday with just some bruises and a sprained ankle.
Kubica said on Thursday he felt 100 per cent ready to race, but the FIA doctors have not given the Pole the green light.
He was rejected on grounds of fears of another impact that could cause him another concussion so soon after his previous one.
He will undergo further checks in France before he is allowed to compete again.
"I am disappointed especially as I feel so good," said Kubica, who will fly home instead of staying at the track for the Grand Prix.