Pippa Mann will reunite with Dale Coyne Racing to drive the team's third entry in this month's Indianapolis 500.
The Brit, who made four starts with DCR last year, will pilot the team's #63 car, and will carry an all-pink helmet and car livery in recognition of leading breast cancer organisation Susan G. Komen.
Her entry will be engineered by Brandon Fry, who previously worked with Mann during her Indy debut in 2011.
"Dale Coyne Racing has an amazing crew coming on board to staff the #63 car, and I can't thank Dale and the team enough for their support of this project, and for all the hard work they have also put into this behind the scenes," said Mann.
"We will be out there not only racing for position, and competing in a classic racing sense against our competitors on track, but we will also be out there racing for the cure."
Mann has not raced since her outing with Coyne at Fontana last year.
Her best result at Indy was a 20th in 2011 with Conquest, while her highest finish from her six IndyCar starts was 15th at Pocono last July.